Any% aims to finish the game as fast as possible. In this category lethal weapon strategies against enemies are used, alerts taken in favor for faster walking lines and ignoring most laser traps and explosives by becoming a zombie snake. The biggest skip is not grabbing the Nikita weapon in the armory and not having to shoot the 3 sensors in B2 to continue directly to the Engineering room.
»> Video explanation for Zombie Snake
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Technically lethal can be faster. While shooting the guards only takes 1 lethal shot vs 2 non-lethal shots (most of the time), it will even out with the delay of opening the door. When killing the guards in a lethal matter, they will need to despawn first before the door opens. In that time Snake can move closer to the door. Non-Lethal takedowns don't require the guards to despawn to have the door open, but snake also needs to walk further. If a way is found to consistently one non-lethal shot both guards in this hallway, non-lethal can be faster.