Table of Contents

MGS:PO New Game Any% Routes & Guide

v1.20 by MarlonH8


Goal: Start a new save file and complete the game as fast as possible

Pre-Run

Useful Knowledge

Noteworthy Techniques and Notations

Notes Regarding Difficulty-Specific Strategies

While the main route presented in this guide is based on the NORMAL Difficulty, most of these strategies and routes work identically on their EASY counterparts.
If there are exclusive alternatives available to either Difficulty, they will be marked by the following tags: [EASY], [EASY-only] & [NORMAL-only].
All of these occurences are also listed below:

Stage Routing Change
Hospital EASY: Guard has much lower stamina → “PP-PPK Route” is recommended
Airport EASY: No terminal guard → Make use of the “Direct Route” instead
Silo Entrance III. EASY: No need for additional Stun Gs → Use the “Straight2Complex Route”
Silo Complex NORMAL: Additional guard in front of locked door #2 → Alternative “2-Codec Route” is now viable

All bosses deal less damage, but otherwise behave in the exact same manner on EASY. The other important difference lies in the amount of health & stamina that you can drain per hit.
This is usually1) increased by 50% on EASY. All in all, this enables EASY speedruns to finish just over a minute earlier than a NORMAL run would.
The fastest, reliable boss strategies for EASY are listed below:

Python Null 1 RAXA Null 2 Cunningham Gene

[I] Escape & Diversionary Operations

[1.1] Prison

Standard Route

Further Information & Strategies

Double Handle Grab

You can skip one of the cell door handle grab animations here. In order to do that, you need to run towards the door's handle in a way that places yourself just out of range to normally initiate the door opening animation when pressing the action button.
If properly executed, this precise trick makes one handle grab count as two or more and therefore advances Snake straight to the text box. The skip was discovered by Pythonicus during his first full speedrun!

[1.2] Comm Base I.

Standard Route

Briefing Menu

Action Input
Fast forward Dialogue
Select Soviet Patrol Base
Fast forward Dialogue
Start Mission

Alternative Routes

Legacy Route (<1s timeloss)
Marginally slower, but extremely safe

[2] Soviet Patrol Base I.

Standard Route

Briefing Menu

Action Input
Fast forward Dialogue
Select Supply Depot
Fast forward Dialogue
Start Mission

Further Information & Strategies

Cutscene/Text Triggers

Cutscene or Text Triggers like the one here temporarily block you from moving. If you enter the trigger area with a roll, your animation will carry you a bit further.

Alternative Routes

Crate Roll Route (<1s timesave) Ultimate Precision Route (2+s timesave)
Semi-precise optimization Near TAS-like precision needed! - not recommended!

[3] Supply Depot I.

Standard Route

Briefing Menu

Action Input
Fast forward Dialogue
Jonathan → Sneaking Unit - Team Alpha #1 ← ↓ Square → ↓ Square Square ↑ Square
Select Comm Base
Fast forward Dialogue
Select Comm Base
Fast forward Dialogue
Start Mission

Further Information & Strategies

Inventory Bloat [1/2]

If you find yourself accidentally picking up unnecessary items such as the 9mm T Ammo dropped by Jonathan here, make sure to drop (Inventory, Drop [L]) or replace it at the next opportunity.
Inventory bloat can lead to additional timeloss later on so it's best to proactively prevent it from happening.

Truck Recruitment Positioning

Make sure to not drag soldiers too close to the truck's rear. Snake will always go towards a fixed spot, which is a certain distance behind the truck.
If you entered the trigger zone from an unfavorable position, you could lose valuable seconds due to longer animations.

Why Supply Depot?

While the game recommends you to go to the Soviet Patrol Base, you can actually visit any of the available stages to complete this recruitment mission.
We're simply recruiting this soldier on this stage, because he is closer to our truck and therefore faster to drag there than anyone else. The TNT pickup is an added bonus.

[4] Comm Base II.

Standard Route

Briefing Menu

Action Input
Fast forward Dialogue
Select Hospital
Fast forward Dialogue
Start Mission

[5] Hospital

Standard Route

Briefing Menu

Action Input
Fast forward Dialogue
Select Research Lab
Fast forward Dialogue
Start Mission

Further Information & Strategies

Inventory Bloat [2/2]

If you find yourself accidentally picking up an item dropped by the Recruit here, make sure to drop (Inventory, Drop [L]) or replace it at the next opportunity.
Inventory bloat can lead to additional timeloss later on so it's best to proactively prevent it from happening.

CQC Slam vs. 180-BG

While performing a slam to knock out guards like this once can theoretically be faster, it comes with other drawbacks and risks. There's a very high chance that the soldier will have enough stamina to take one CQC slam without falling unconscious.
This chance is drastically lower, but still present on EASY difficulty. Additionally, you will be out of range to instantly pause and perform a Member Change without repositioning here, thus losing further time.

"Why recruit this guy at all?"

While it is technically possible to finish the run without any additional recruitments, the impact it would have on Spy Report RNG is huge. The chance of saving time by skipping this Recruit and relying on amazing Spy Report luck lingers in the one digit range (x%).

A Man Who Delivers

The soldier obtained after Jonathan (Recruit) will always have the Deliveryman skill.

Alternative Routes

[EASY-only] PP-PPK Route (3+s timesave)
Exclusive to EASY - making use of the soldier's lower stamina

[6] Research Lab I.

Standard Route

Briefing Menu

Action Input
Fast forward Dialogue
Confirm & fast forward Dialogue if Recruit persuaded here [1/4]
Jonathan → Spy Unit - Supply Depot Square → R R Square
Recruit → Spy Unit - Research Lab [1/4] @Spy Unit ← ← ↑ ↑ Square → → ↑ Square
Wait once for Supply Depot Report
Read it & fast forward Dialogue
Select Supply Depot ↓ ↓ ↓
Fast forward Dialogue
Start Mission

Alternative Routes

Swapless Route (2+s timeloss IGT/1+s timesave RTA)
Same route minus the Member Change

[7] Supply Depot II.

Standard Route

Briefing Menu

Action Input
Fast forward Dialogue
Confirm & fast forward Dialogue if Recruit persuaded here [2/4]
Recruit → Spy Unit - Research Lab [2/4] @Sneaking Unit ← ↑ ↑ Square → → ↑ L L Square
Select Rail Bridge
Fast forward Dialogue
Start Mission

[8] Rail Bridge I.

Standard Route

Briefing Menu

Action Input
Fast forward Dialogue
Confirm & fast forward Dialogue if Recruit persuaded here [3/4]
Recruit → Spy Unit - Research Lab [3/4] @Sneaking Unit ← ↑ ↑ Square → → ↑ L L Square
Wait for Supply Depot Report (or Research Lab Report)
Read it & fast forward Dialogue
Jonathan (or Recruit) → Spy Unit - Soviet Patrol Base @Sneaking Unit → R R Square R Square (or ← ↑ ↑ Square → → R R R Square)
RECOMMENDED: Use up all your Waits (will improve Spy Report acquisition rate)
Select Supply Depot (or Research Lab) ↓ ↓ ↓ (or ↑ ↑)
Fast forward Dialogue
Start Mission

Further Information & Strategies

Further Expanding Upon Great Report Luck [1/2]

If you find yourself in the uncommon situation that you already have two of the three necessary Spy Reports before launching into your first Diversionary Mission, you can expand on your luck even further.
In order to do that, assign both Jonathan and the Recruit to the leftover Spy Report location to boost its Report acquisition rate.

Order of Diversionary Mission Completions

For the TNT-blowup missions (9-A, 9-B, 9-C [& 9-D]) the order in which you read and complete the Spy Reports can help you save around a second by skipping some pre-deployment dialogue.
If you receive more than one TNT Report during a Briefing session, make sure to read the canonically later one first. Then, read the other one(s) and complete the last Report, which you've read.
The canon timeline looks like this: [Town >] SPB > RL > SD
Examples: If you get both RL & SD Reports, read RL first, then read and complete SD. If you receive Reports for SPB & RL, read SPB before reading and completing RL.
After finishing three of these missions, you can move on to [10] Rail Bridge II.!

[9-A] Supply Depot III.

Standard Route

Briefing Menu

Action Input
Fast forward Dialogue
Confirm & fast forward Dialogue if Recruit persuaded here [4/4]
Recruit → Spy Unit - Research Lab [4/4] @Sneaking Unit ← ↑ ↑ Square → → ↑ L L Square
If this was your 3rd Diversionary Op: Select Rail Bridge, fast forward Dialogue & start Mission
Wait for Research Lab Report (or Soviet Patrol Base Report)
Read it & fast forward Dialogue
RECOMMENDED: Use up all your Waits (if this was your 1st or 2nd Diversionary Op)
Select Research Lab (or Soviet Patrol Base) ↓ ↓ ↓ (or ↓)
Start Mission

Further Information & Strategies

Further Expanding Upon Great Report Luck [2/2(A)]

If you find yourself in the uncommon situation that you already have two of the three necessary Spy Reports before launching into your second Diversionary Mission, you can expand on your luck even further.
In order to do that, assign both Jonathan and the Recruit to the leftover Spy Report location to boost its Report acquisition rate.

[9-B] Research Lab II.

Standard Route

Briefing Menu

Action Input
Fast forward Dialogue
If this was your 3rd Diversionary Op: Select Rail Bridge, fast forward Dialogue & start Mission
Wait for Soviet Patrol Base Report (or Supply Depot Report)
Read it & fast forward Dialogue
RECOMMENDED: Use up all your Waits (if this was your 1st or 2nd Diversionary Op)
Select Soviet Patrol Base (or Supply Depot) ↑ ↑ (or ↑ ↑ ↑)
Start Mission

Further Information & Strategies

Further Expanding Upon Great Report Luck [2/2(B)]

If you find yourself in the uncommon situation that you already have two of the three necessary Spy Reports before launching into your second Diversionary Mission, you can expand on your luck even further.
In order to do that, assign both Jonathan and the Recruit to the leftover Spy Report location to boost its Report acquisition rate.

[9-C] Soviet Patrol Base II.

Standard Route

Briefing Menu

Action Input
Fast forward Dialogue
If this was your 3rd Diversionary Op: Select Rail Bridge, fast forward Dialogue & start Mission
Wait for Supply Depot Report (or Research Lab Report)
Read it & fast forward Dialogue
RECOMMENDED: Use up all your Waits (if this was your 2nd Diversionary Op)
Select Supply Depot (or Research Lab) ↑ ↑ (or ↑ ↑ ↑)
Start Mission

Further Information & Strategies

Further Expanding Upon Great Report Luck [2/2(C)]

If you find yourself in the uncommon situation that you already have two of the three necessary Spy Reports before launching into your second Diversionary Mission, you can expand on your luck even further.
In order to do that, assign both Jonathan and the Recruit to the leftover Spy Report location to boost its Report acquisition rate.

TNT Diversionary Operation... D?!

There is one more location in which you could perform a diversionary operation; Town! However, since it has by far the slowest route it is in no way viable for the run.

Briefing Menu (Post-Diversionary Ops)

Action Input
Fast forward Dialogue
Fast forward Dialogue if Campbell says “Hey Snake…” here [1/5]
Select Rail Bridge
Fast forward Dialogue
Start Mission

[10] Rail Bridge II.

Standard Route

Briefing Menu

Action Input
Fast forward Dialogue
Fast forward Dialogue if Campbell says “Hey Snake…” here [2/5]
Select Harbor
Fast forward Dialogue
Start Mission

Alternative Routes

Diversionary Shot Route (1+s timeloss)
Any Tsuchinoko run's go-to strategy

[II] New Friends, Loose Ends

[11] Harbor

Standard Route

Briefing Menu

Action Input
Fast forward Dialogue
Fast forward Dialogue if Campbell says “Hey Snake…” here [3/5]
Jonathan + Recruit → Spy Unit - Security Base ← ↓ Square → → ↑ Square Square ← ← ↑ ↑ Square
Wait for Security Base Report
Read it & fast forward Dialogue
Select Security Base
Fast forward Dialogue
Start Mission

Further Information & Strategies

NTSC vs PAL

Unlike on PAL, the cutscene trigger won’t save you from taking fall damage in the NTSC releases.

Alternative Routes

Sneaky Route (3+s timeloss) Pick up M63 (7+s timeloss*)
Strategies from this route can be mixed in as desired Alternative to Jonathan's AK-47 and Stun Gs for Cunningham - *has a slim chance of saving up to 7s total on Cunningham

[12] Security Base

Standard Route

Briefing Menu

Action Input
Fast forward Dialogue
Fast forward Dialogue if Campbell says “Hey Snake…” here [4/5]
Select Warhead Storage
Fast forward Dialogue
Start Mission

Alternative Routes

Sneaky Route (2+s timeloss)
Strategies from this route can be mixed in as desired

[13.1] Warhead Storage

Standard Route

Further Information & Strategies

Ensuring a Successful Infrared Sensor Bait

The infrared sensors present throughout the whole facility always run north/southwards and will alert everyone simultaneously once triggered!
For the Standard Route it does not matter if you prematurely get spotted by the female officer before arriving at the tunnel, however it is important to only trigger this one set of sensors.
If you trigger any other sensors beforehand or get kicked down by the officer, you can easily lose the Alert Phase and therefore your trail while continuing through the level.

Alternative Routes

Simple Route (20+s timeloss)
The fastest option without planting additional TNT

[13.2] Python Boss Fight

Standard Route

Briefing Menu

Action Input
Fast forward Dialogue
Fast forward Dialogue if Campbell says “Hey Snake…” here [5/5]
Wait for Security Base Report
Read it & fast forward Dialogue
Jonathan → Sneaking Unit - Team Alpha #2 ← ↓ Square → ↓ Square
Equipment (Jonathan): Unequip AK-47 [] [?] [] []
Equipment (Snake): Unequip Mosin N, equip AK-47 onto TNT [Mk22] [AK-47] [] []
Select Airport
Start Mission

Further Information & Strategies

FPV Lookdown Exploit

Looking down while in FPV mode prevents most enemies' incoming fire from hitting you, This works, because looking down in FPV seems to turn your plane of a hurtbox parallel to the ground. Since this strategy was discovered in 2017 by MarlonH8 it fundamentally made the game much easier than it was before - from both a speedrun and casual perspective.

Python's RNG

Python will react differently to incoming damage. Ideally, you'd want to see his long recovery animation that barely leaves any room for him to retaliate, but this is rarely the case.

"Safe" Python

If you get on top of one of the metal cages you'll have a much safer, but also much slower time taking out Python.

[14] Airport

Standard Route

Briefing Menu

Action Input
Fast forward Dialogue
Wait until Daytime if necessary (Stun G only spawns at Day)
Select Silo Entrance
Fast forward Dialogue
Start Mission

Further Information & Strategies

The Terminal Guard

Depending on when and where you shoot to spook the upper soldier he may switch his position to either next to the terminals or the northern, eastern or southern side of the pillar to call for backup. A quick hold up while passing by helps elminate the possibility of him spotting you.

Top to Bottom Lure Strat

You can lure the topmost guard outside - opening the ID-locked door for you. It's a minimum of 18s slower than the “swap-strat”.

Alternative Routes

[EASY-only] Direct Route (1+s timesave) Risky Route (1+s timesave) Classic Solo Route (9+s timeloss)
Exclusive to EASY - no terminal guard The soldier can easily shoot the official, therefore failing the mission No member-swapping involved!

[15.1] Silo Entrance I.

Standard Route

Alternative Routes

Roll Rush (<1s timesave) Ladder Rush (<1s timeloss) Sneaky Route (2+s timeloss)
Marginally faster alternative if you're willing to tank more damage Slightly slower alternative if you're willing to tank more damage Undetected - used for Tsuchinoko runs

[15.2] Null Boss Fight I.

Standard Route

Briefing Menu

Action Input
Fast forward Dialogue
Select Silo Entrance
Fast forward Dialogue
Select Team & start Mission

Further Information & Strategies

M63/AK-47/M16A1 vs. RPG-7 Comparison

27+s are saved by using weapons like the M63, AK-47 or M16A1 over the RPG-7 for both Null fights.

[16] Silo Entrance II.

Standard Route

Briefing Menu

Action Input
Fast forward Dialogue
Select Rail Bridge ↑ ↑ ↑ ↑ ↑ ↑
Fast forward Dialogue
Select Team & start Mission

Alternative Routes

Risky “Oof” Strats v2 (1+s timesave)
RKD on guard while dropping below - “Oof” when failed

[17] Rail Bridge III.

Standard Route

Briefing Menu

Action Input
Fast forward Dialogue
Select Guest House
Fast forward Dialogue
Select Team & start Mission

Further Information & Strategies

History of the "Spy Report Skip"

Here, we are performing a sequence break - accidentally discovered by miniomegaking. While watching one of mini's Rail Bridge route videos, MarlonH8 noticed that the guard patterns were different. Originally assumed to be either regional differences, the oddity was shortly thereafter explained by the fact that mini forgot to place spies in the area to notify him of the report and therefore skipped one step ahead.
Immediately afterwards, we tried to find similar spy report skips, but didn't have much luck. MarlonH8 did find another one for the Town Diversionary Op., which unfortunately is the slowest of the “TNT-missions” and therefore not part of the run.

[18] Guest House

Standard Route

Briefing Menu

Action Input
Fast forward Dialogue
Swap Jonathan with Snake Square ← Square
Recruit + Python → Spy Unit - Silo Entrance @All ↓ ↓ Square → → ↑ Square Square ← ← ↑ ↑ Square
Select Plant
Fast forward Dialogue
Start Mission

Further Information & Strategies

Healthy Snake

Snake will be fully healed after being rescued.

[19.1] Plant

Standard Route

Alternative Routes

Diversionary Shot Route (<1s timeloss)
Tsuchinoko's top tier strategy

[19.2] Metal Gear RAXA Boss Fight

Standard Route

Briefing Menu

Action Input
Confirm & fast forward Dialogue
Wait for Silo Entrance Report
Read it & fast forward Dialogue
Recruit + Python → Spy Unit - Ravine → ↑ L Square ↓ Square Square ↑ Square
Wait for Ravine Report
Read it & fast forward Dialogue
Recruit + Python → Technical Unit ← ↓ Square → → → Square ↓ Square ← ← ← ↑ ↑ Square
Select Ravine
Fast forward Dialogue
Start Mission

Further Information & Strategies

Extra Ammo (HEAT)

There is an RPG-7 with 10 loaded rockets found towards the northeast and an additional box of Ammo (HEAT) x20 found in the southern end of the hall.

TX-55 Strats

Originally, we also used to damage RAXA's legs with TNT. At that time, we were still using the RPG-7 vs. Null and therefore entered this fight with little to no ammo.

Jonathan's Inventory

Jonathan’s items do NOT get lost after his sacrifice. You will be able to reequip them if so desired.

Alternative Routes

No RPG-7 Start (20+s timeloss)
Picking up the RPG-7/ammo during the fight

[III] Lights Out and Away We Go

[20] Ravine

Standard Route

Briefing Menu

Action Input
Fast forward Dialogue
Select Power Substation
Fast forward Dialogue
Start Mission

Further Information & Strategies

No Fall Damage

At the cost of a few seconds, the fall damage of the Standard Route can be mitigated by rolling over the railing earlier.

Alternative Routes

Slow Descent Route (<1s timeloss)
An alternative path leading to similar results

[21] Power Substation I.

Standard Route

Briefing Menu

Action Input
Fast forward Dialogue
Wait for Detonation Timer development to “begin”
Confirm it & fast forward Dialogue
Equipment (Snake): Equip Time Bomb onto Mk22 [Time Bomb] [AK-47] [RPG-7/Med Kit S] [Stun G]
Python → Sneaking Unit - Team Alpha #2 ↓ Square ← ↑ ↑ Square
Select Power Substation
Fast forward Dialogue
Start Mission

Further Information & Strategies

Why unequip the Mk22 and menu in Python?

Unlike on other routes, we don't have the need to make it through the Silo Entrance and Complex silently. With no use for Mk22 shots to distract guards, better routes are now available.
By putting Python into Team Alpha's Slot #2, we skip any further Unit Management later on and save a good second this way.
Python is chosen over the Recruit, because only he has a fixed CQC Rank of B, which is necessary to perform grabs on enemies. Additionally, him having a faster stalk shaves off bonus frames.

[22.1] Power Substation II.

Standard Route

Alternative Routes

Drop Route (<1s timeloss)
Just another alternative path

[22.2] Null Boss Fight II.

Standard Route

Briefing Menu

Action Input
Fast forward Dialogue
[NORMAL] Wait until Daytime if necessary (Stun G only spawns at Day)
Select Silo Entrance
Fast forward Dialogue
Start Mission

[23] Silo Entrance III.

Standard Route

Briefing Menu

Action Input
Fast forward Dialogue
Select Silo Complex
Fast forward Dialogue
Start Mission

Further Information & Strategies

Possible Ladder Route

While a strategy similar to SE1's alternative “Ladder Rush” is doable, you'd be putting yourself at a big disadvantage by going on such a route.
Some guards in the area are also equipped with shotguns, which can easily cost you seconds when getting hit and knocked down.

Alternative Routes

[EASY] Straight2Complex Route (12+s timeloss throughout the run*)
Skip Stun G pickups - *16+s timesave on EASY

[24] Silo Complex

Standard Route

PAL/Guard Route NTSC/Key Route
Head forward and right, then stalk up to the FOX soldier behind the crates Head forward past the pillar and crates, then continue right and take a left
Grab, then drag him to the door you just passed to gain temporary access Escape through the door to the hall and cross the southern and eastern gaps with rolls
Push-drop him and run inside to bump into the guard between the walls on the left Pick up Key E, then exit the way you came from and head to the door north of you
Quickly advance through the door next to him Avoid the soldier's shotgun fire and rush through the door behind him

Briefing Menu

Action Input
Fast forward Dialogue
Select Silo Complex
Fast forward Dialogue
Start Mission

Further Information & Strategies

PAL vs. NTSC

Arguably the biggest version difference of the run is right here. On NTSC versions you can not drag any soldier in front of the 1F door to open it.

Ghost Codec

Opening your contact list and calling Ghost saves time compared to manually tuning to 145.75 from 140.85. Ghost's frequency (144.78) lets you skip closer to 145.75.

Door Frequencies

145.75 is used on all routes to get you through the locked 1F door in the room behind the “wall guard”.
147.42 is used on most routes to get past the 2F door leading onto the bridge without having to drag a guard all the way over there.
148.51 is used on routes triggering an Alert Phase, as it lets you rush past the final soldier instead of having to deal with him.

Alternative Routes

3-Codec Route + Heals (8+s timeloss) [NORMAL-only] 2-Codec/“ + Heals (<1s timesave/8+s timeloss) NTSC Key Route/” + Heals (7+s/15+s timeloss)
Additional heals for those who want to play it safe Uses the guard present on NORMAL instead of calling 147.42 NTSC's fastest option

[25] Cunningham Boss Fight

Standard Route

If Cunningham is moving to your left If Cunningham is moving to your right
Quickly throw 2 Stun Gs close to him at the platform's left corner Quickly throw 3 Stun Gs close to him, central of the platform's edge in front of you
Continue throwing another 2 Stun Gs whenever he says “Here, mousy, mousy!” or “Eat THIS!” If he says “Here, mousy, mousy!” or “Eat THIS!”, continue throwing the remaining Stun Gs to finish him off
Otherwise wait for him to arrive at his next position before finishing him off Otherwise wait for him to arrive and talk at his next position before finishing him off

Briefing Menu

Action Input
Fast forward Dialogue
Select Launch Control Room
Fast forward Dialogue
Start Mission

Further Information & Strategies

Extra Ammo

A box of ammo drops at the very beginning of the fight. The type of ammo is based on whichever weapon you have equipped before it falls to the ground.
This can come in handy if you are running low on AK-47 ammo (7.62x39mm) for the upcoming fight against Gene.

Reload Animation Cancels/Quick Reloads

You can cancel most reload animations and still have your ammo refilled. You do this by moving close enough to any kind of barrier for it to block you from aiming your weapon.
This works especially well in FPV-mode, but even here in TPV the railings make this strategy work like a charm with the MK22 and auto-aim!

Increased Accuracy + Trivia

As with most weapons, firing while crouched significantly increases the player's accuracy. This is especially useful for the classic M63 strategies here.
On August 5 2018, three hours before a #MGSR MPO race stream between Pythonicus and MarlonH8, the latter “rediscovered” this detail, which lead to both runners defeating Cunningham a whopping minute earlier than what was expected at the time.

Outdated Legacy Routes

5 x Stun G + M63 + 7 x MK22 (24+s timeloss throughout the run) - Part of the 1 Stun G pack Route.
M63 + 40 x MK22 (53+s timeloss throughout the run) - Variation of the original, outdated go-to strategy.
9 x RPG-7 + 40 x MK22 (44s+ timeloss throughout the run) - The original, outdated go-to strategy.

Alternative Routes

Hover Gamble (1+s timesave) M63 Lethal (6+s timeloss throughout the run*) 5 x Stun G + 3 x RPG-7 + 7 x MK22 (16+s timeloss throughout the run*)
Relying on Cunningham staying stationary - High risk on Easy (1 Stun G Route) *If you get insanely lucky accuracy, you can skip a phase and save 6+s total *When on 1 Stun G Route, you may only lose 2+s instead

[26] Gene Boss Fight

Standard Route

Further Information & Strategies

Extra Ammo

Should you find yourself running low on ammo, an additional ammo pickup will spawn in the northwestern corner of the room.

Emulator Crash Trivia

On PPSSPP versions prior to 1.4 Gene dashing towards the northern & southern terminals would cause the emulator to crash!

Alternative Routes

Classic Gene (23+s timeloss) Classic Non-Lethal Gene (43+s timeloss throughout the run)
No cheese - the go-to lethal strat pre-September '22 No cheese - Mosin N + Mk22 - equip Mosin N onto Stun G post-PS1

RUN COMPLETED!

Return to MPO

1)
Stun Gs are affected to a lesser degree. This is noticeable on bosses like Cunningham, who still needs 5 instead of 6 hits to be defeated.